Adipocytokines and autoimmunity
نویسندگان
چکیده
منابع مشابه
Adipocytokines and Hepatic Fibrosis
Obesity and metabolic syndrome pose significant risk for the progression of many types of chronic illness, including liver disease. Hormones released from adipocytes, adipocytokines, associated with obesity and metabolic syndrome, have been shown to control hepatic inflammation and fibrosis. Hepatic fibrosis is the final common pathway that can result in cirrhosis, and can ultimately require li...
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Adipose tissue-produced hormones significantly affect the metabolism of lipids and carbohydrates as well as numerous other processes in human body. It is generally accepted that endocrine dysfunction of adipose tissue may represent one of the causal links between obesity and insulin resistance/diabetes. Epidemiological studies underlined that obesity represents a significant risk factor for the...
متن کاملAdipocytokines and Insulin Resistance
I t is well known that adipocytes and resident macrophages that have migrated to adipose tissue produce and secrete a variety of biologically active mediators (adipocytokines), which are thought to contribute to the development of insulin resistance, type 2 diabetes, and cardiovascular disease (1). The abnormal function of adipocytes may play an important role in the development of a chronic lo...
متن کاملObesity, Adipocytokines and Cancer
A great amount of literature has demonstrated a connection between obesity, visceral fat and the metabolic disorders such as hyperglycemia, hypertension, and hyperlipidemia. Lately, there has been an increased interest in understanding if cancer is related to obesity and visceral fat accumulation. The prevalence of both obesity and cancer are increasing and there has been keen interest in the r...
متن کاملAdipocytokines and obesity-linked disorders.
Obesity is closely associated with an increased risk for metabolic and cardiovascular diseases. Adipose tissue produces a number of secretory bioactive substances, also known as adipocytokines or adipokines, which directly affect adjacent or distant organs. Most adipocytokines are pro-inflammatory, thereby promoting the obesity-linked disorders. In contrast, there are a small number of adipocyt...
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ژورنال
عنوان ژورنال: Arthritis Research & Therapy
سال: 2011
ISSN: 1478-6354
DOI: 10.1186/ar3412